BDBM376483 (R)-N-(1-(3- methoxyphenyl)ethyl)-9H- pyrido[3,4-b]indole-7- carboxamide::US9914740, XIV-4

SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1ccc2c(c1)[nH]c1cnccc21

InChI Key InChIKey=LCXPFCGRIBLRQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376483   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376483(US9914740, XIV-4 | (R)-N-(1-(3- methoxyphenyl)ethy...)
Affinity DataIC50: 1.29nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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