BDBM376456 N-[(1S)-2-hydroxy-1- phenylethyl]-6,6- dimethyl-6H- isochromeno[3,4-c] pyridine-8-carboxamide::US9914740, XI-31

SMILES CC1(C)Oc2cnccc2-c2ccc(cc12)C(=O)N[C@H](CO)c1ccccc1

InChI Key InChIKey=SBSYPAHUAKCDFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376456   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376456(US9914740, XI-31 | N-[(1S)-2-hydroxy-1- phenylethy...)
Affinity DataIC50: 1.44nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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