BDBM376377 US9914740, VIII-3::US9914740, XI-20::US9914740, XI-21

SMILES CCC1Oc2cnccc2-c2ccc(cc12)C(=O)NCc1cccc(c1)C(=O)NCC(C)(C)O

InChI Key InChIKey=HUVFRIYWNZIEHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 376377   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376377(US9914740, XI-20 | US9914740, XI-21 | US9914740, V...)
Affinity DataIC50: 0.650nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376377(US9914740, XI-20 | US9914740, XI-21 | US9914740, V...)
Affinity DataIC50: 1.81nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376377(US9914740, XI-20 | US9914740, XI-21 | US9914740, V...)
Affinity DataIC50: 1.99nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent