BDBM376374 N-(4-fluoro-3- (2-hydroxy- 2-methyl- propylcarbamoyl) benzyl)-6H- isochromeno::US9914740, VII-12

SMILES CC(C)(O)CNC(=O)c1cc(CNC(=O)c2ccc-3c(COc4cnccc-34)c2)ccc1F

InChI Key InChIKey=DQKGGNWLPPOHTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376374   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376374(US9914740, VII-12 | N-(4-fluoro-3- (2-hydroxy- 2-m...)
Affinity DataIC50: 1.82nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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