BDBM376305 N-(3- (ethylcarbamoyl) benzyl)-5H- chromeno[3,4-c] pyridine-8- carboxamide::US9914740, III-5

SMILES CCNC(=O)c1cccc(CNC(=O)c2ccc-3c(OCc4cnccc-34)c2)c1

InChI Key InChIKey=QTSFFESNVBCXPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376305   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376305(US9914740, III-5 | N-(3- (ethylcarbamoyl) benzyl)-...)
Affinity DataIC50: 2.54nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent