BDBM376116 N-(3-((2,5-dioxoimidazolidin- 1-yl)methyl)-1-(4- fluorophenyl)-1H-pyrazol-5- yl)-2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 112

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(CN3C(=O)CNC3=O)nn2-c2ccc(F)cc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=AGDLASQMWHJNQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376116   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376116(US9914736, Compound 112 | N-(3-((2,5-dioxoimidazol...)
Affinity DataIC50: 1.90nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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