BDBM376112 2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(6-oxo-2- phenyl-4,5,6,7-tetrahydro-2H- pyrazolo[4,3-c]pyridin-3-yl)- 4-(trifluoromethyl)benzamide::US9914736, Compound 108

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2c3CNC(=O)Cc3nn2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=LPEFDPNRPMBWJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376112   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376112(US9914736, Compound 108 | 2-fluoro-5-(1-methyl-1H-...)
Affinity DataIC50: 4.60nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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