BDBM376107 N-(3-(3- (aminomethyl)phenyl)-1-(4- fluorophenyl)-1H-pyrazol-5- yl)-2-fluoro-5-(pyrimidin-2- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 103

SMILES NCc1cccc(c1)-c1cc(NC(=O)c2cc(-c3ncccn3)c(cc2F)C(F)(F)F)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=AJKJPVCJYIRAGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376107   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376107(US9914736, Compound 103 | N-(3-(3- (aminomethyl)ph...)
Affinity DataIC50: 2.40nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
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Date in BDB:
1/30/2020
Entry Details
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