BDBM376102 N-(1-(4-fluorophenyl)-3-((2- oxo-1,2-dihydropyridin-3- yl)methyl)-1H-pyrazol-5-yl)- 3-(1-methyl-1H-pyrazol-3-yl)- 4-(trifluoromethyl)benzamide::US9914736, Compound 98

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(Cc2ccc[nH]c2=O)nn1-c1ccc(F)cc1

InChI Key InChIKey=KKKYHGGKAYSJOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376102   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376102(US9914736, Compound 98 | N-(1-(4-fluorophenyl)-3-(...)
Affinity DataIC50: 3.80nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
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Date in BDB:
1/30/2020
Entry Details
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