BDBM376100 N-(3-((1H-pyrazol-3- yl)methyl)-1-(4-fluorophenyl)- 1H-pyrazol-5-yl)-3-(1-methyl- 1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 96

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(Cc2cc[nH]n2)nn1-c1ccc(F)cc1

InChI Key InChIKey=VVNFHLGLIMUJCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376100   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376100(US9914736, Compound 96 | N-(3-((1H-pyrazol-3- yl)m...)
Affinity DataIC50: 3.70nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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