BDBM3761 Benzothieno[3,2-d]pyrimidine deriv. 52::CHEMBL103014::N-[(1R)-1-phenylethyl]-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine

SMILES C[C@@H](Nc1ncnc2c3ccccc3sc12)c1ccccc1

InChI Key InChIKey=WXXYNGFRGPWDFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3761   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3761(N-[(1R)-1-phenylethyl]-8-thia-3,5-diazatricyclo[7....)
Affinity DataIC50: 538nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3761(N-[(1R)-1-phenylethyl]-8-thia-3,5-diazatricyclo[7....)
Affinity DataIC50: 538nMAssay Description:Inhibition of EGF-induced Tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed