BDBM376089 2-fluoro-N-(1-(4- fluorophenyl)-3-((2-methyl- 2H-tetrazol-5-yl)methyl)-1H- pyrazol-5-yl)-5-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 85

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(Cc3nnn(C)n3)nn2-c2ccc(F)cc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=CEXUKBVSWSLTNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376089   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376089(US9914736, Compound 85 | 2-fluoro-N-(1-(4- fluorop...)
Affinity DataIC50: 1.20nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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