BDBM376080 5-({[2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)phenyl] carbonyl}amino)-5'-methyl-N- (pyridin-3-ylmethyl)-2'H-1,3'- bipyrazole-3-carboxamide::US9914736, Compound 76

SMILES Cc1cc([nH]n1)-n1nc(cc1NC(=O)c1cc(-c2ccn(C)n2)c(cc1F)C(F)(F)F)C(=O)NCc1cccnc1

InChI Key InChIKey=XDXOKUFRXCDTQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376080   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376080(US9914736, Compound 76 | 5-({[2-fluoro-5-(1-methyl...)
Affinity DataIC50: 0.390nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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