BDBM376071 3-(1-methyl-1H-pyrazol-3-yl)- N-[1-phenyl-3-(2H-tetrazol-2- ylmethyl)-1H-pyrazol-5-yl]-4- (trifluoromethyl)benzamide::US9914736, Compound 67

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(Cn2ncnn2)nn1-c1ccccc1

InChI Key InChIKey=MDHXKMUPTFDAEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376071   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376071(US9914736, Compound 67 | 3-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 3.70nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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