BDBM376069 2-fluoro-N-(1-methyl-3- phenyl-1H-pyrazol-4-yl)-5-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 65

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cn(C)nc2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=WLRKTFXVPQZEDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376069   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376069(US9914736, Compound 65 | 2-fluoro-N-(1-methyl-3- p...)
Affinity DataIC50: 4.5nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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