BDBM376063 2-chloro-5-(1-methyl-1H- pyrazol-3-yl)-N-{3-[(1- methyl-1H-tetrazol-5- yl)methyl]-1-phenyl-1H- pyrazol-5-yl}-4- (trifluoromethyl)benzamide::US9914736, Compound 59::US9914736, Compound 80

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(Cc3nnnn3C)nn2-c2ccccc2)c(Cl)cc1C(F)(F)F

InChI Key InChIKey=RMSZUVDFSNCVNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376063   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376063(US9914736, Compound 59 | US9914736, Compound 80 | ...)
Affinity DataIC50: 1.70nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376063(US9914736, Compound 59 | US9914736, Compound 80 | ...)
Affinity DataIC50: 0.780nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent