BDBM376062 2-chloro-5-(1-methyl-1H- pyrazol-3-yl)-N-{3-[(2- methyl-2H-tetrazol-5- yl)methyl]-1-phenyl-1H- pyrazol-5-yl}-4- (trifluoromethyl)benzamide::US9914736, Compound 58

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(Cc3nnn(C)n3)nn2-c2ccccc2)c(Cl)cc1C(F)(F)F

InChI Key InChIKey=XTAFKNRDKOFSDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376062   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376062(US9914736, Compound 58 | 2-chloro-5-(1-methyl-1H- ...)
Affinity DataIC50: 3.40nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent