BDBM376052 2-chloro-N-(3,5'-dimethyl-1'H- 1,3'-bipyrazol-5-yl)-5-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 48

SMILES Cc1cc(NC(=O)c2cc(-c3ccn(C)n3)c(cc2Cl)C(F)(F)F)n(n1)-c1cc(C)[nH]n1

InChI Key InChIKey=XCCQULQNPTYSGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376052   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376052(US9914736, Compound 48 | 2-chloro-N-(3,5'-dimethyl...)
Affinity DataIC50: 0.820nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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