BDBM376044 4-chloro-3-(1-methyl-1H- pyrazol-3-yl)-N-[3-pyridin-4- yl-5'-(trifluoromethyl)-2'H- 1,3'-bipyrazol-5-yl]benzamide::US9914736, Compound 40

SMILES Cn1ccc(n1)-c1cc(ccc1Cl)C(=O)Nc1cc(nn1-c1cc(n[nH]1)C(F)(F)F)-c1ccncc1

InChI Key InChIKey=BIAWHSWGGJPJPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376044   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376044(US9914736, Compound 40 | 4-chloro-3-(1-methyl-1H- ...)
Affinity DataIC50: 3.20nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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