BDBM376043 2-chloro-N-(1-phenyl-3- pyridin-4-yl-1H-pyrazol-5-yl)- 5-(1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 39

SMILES FC(F)(F)c1cc(Cl)c(cc1-c1cc[nH]n1)C(=O)Nc1cc(nn1-c1ccccc1)-c1ccncc1

InChI Key InChIKey=COLOIUPSEZSVAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376043   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376043(US9914736, Compound 39 | 2-chloro-N-(1-phenyl-3- p...)
Affinity DataIC50: 2.90nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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