BDBM376040 2-chloro-5-(1-methyl-1H- pyrazol-3-yl)-N-(1-phenyl-3- pyridin-4-yl-1H-pyrazol-5-yl)- 4-(trifluoromethyl)benzamide::US9914736, Compound 36

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)-c2ccncc2)c(Cl)cc1C(F)(F)F

InChI Key InChIKey=YPTJLKAUNVFXEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376040   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376040(US9914736, Compound 36 | 2-chloro-5-(1-methyl-1H- ...)
Affinity DataIC50: 0.370nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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