BDBM376032 3-(1-methyl-1H-pyrazol-3-yl)- N-{3-[(6-oxo-1,6- dihydropyridazin-3- yl)methyl]-1-phenyl-1H- pyrazol-5-yl}-4- (trifluoromethyl)benzamide::US9914736, Compound 28

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(Cc2ccc(=O)[nH]n2)nn1-c1ccccc1

InChI Key InChIKey=QVSYZTJYNBXKCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376032   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376032(US9914736, Compound 28 | 3-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 6.60nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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