BDBM376015 3-(1-methyl-1H-pyrazol-3-yl)- N-[3-(6-oxo-1,6- dihydropyridazin-3-yl)-1- phenyl-1H-pyrazol-5-yl]-4- (trifluoromethyl)benzamide::US9914736, Compound 11

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1ccccc1)-c1ccc(=O)[nH]n1

InChI Key InChIKey=SIZGMPWWIDDORY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376015   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376015(US9914736, Compound 11 | 3-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 5.5nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
Go to US Patent