BDBM376010 N-(5'-methyl-3-pyridin-2-yl- 1'H-1,3'-bipyrazol-5-yl)-3-(4- methyl-1,3-thiazol-2-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 6

SMILES Cc1csc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1cc(C)[nH]n1)-c1ccccn1

InChI Key InChIKey=ZQVDZVORZOGMOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376010   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376010(US9914736, Compound 6 | N-(5'-methyl-3-pyridin-2-y...)
Affinity DataIC50: 1.70nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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