BDBM374970 N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(3-fluoro-4-(2-methylpyridin-4-yl)phenyl)acetamide ::US10251893, Cpd 168

SMILES CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2ccc(c(F)c2)-c2ccnc(C)c2)nc1

InChI Key InChIKey=AWWPXGCYXOZMPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374970   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374970(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(3-fl...)
Affinity DataIC50: 0.100nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent