BDBM374917 US10251893, Cpd 125::tert-butyl 4-(6-(2-(4-(2-methylpyridin-4-yl)phenyl)acetamido)pyridin-3-yl)piperazine-1-carboxylate

SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)N2CCN(CC2)C(=O)OC(C)(C)C)cc1

InChI Key InChIKey=LJXAERRBWAZHPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374917   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374917(tert-butyl 4-(6-(2-(4-(2-methylpyridin-4-yl)phenyl...)
Affinity DataIC50: 0.200nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent