BDBM374897 US10251893, Cpd 105

SMILES Fc1cccc(c1)-c1ccc(NC(=O)Cc2ccc(-c3ccnnc3)c(c2)C(F)(F)F)cn1

InChI Key InChIKey=ZFJRAIMVMICCCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374897   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374897(US10251893, Cpd 105)
Affinity DataIC50: 0.110nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent