BDBM374710 US10246462, Example 91

SMILES CNC(=O)[C@@H]1CCCN1[C@H]1CC=C(C[C@H]1C)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N

InChI Key InChIKey=ISQRLBNEGWEANY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374710   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374710(US10246462, Example 91)
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent