BDBM374702 US10246462, Example 83

SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C#N)c2ncc(nc12)C1=CCC([C@H](C)C1)N1CCC[C@H]1C

InChI Key InChIKey=HXCOUSZKZHLJDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374702   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374702(US10246462, Example 83)
Affinity DataIC50: 100nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent