BDBM374680 1-((R)-1-(2,4-Dichlorophenyl)ethyl)-6-(4-fluoro-3′-methyl-[1,4′-bipiperidin]-1′-yl)-3-methyl-1H-pyrazolo[3,4-b]pyrazine hydrochloride::US10246462, Example 61

SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CCC(C(C)C1)N1CCC(F)CC1

InChI Key InChIKey=QKIVRSYBAONDKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374680   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374680(US10246462, Example 61 | 1-((R)-1-(2,4-Dichlorophe...)
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent