BDBM374679 3-((2S)-1-(1-(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-3-methyl-1H-pyrazolo[3,4-b]pyrazin-6-yl)-3-methylpiperidin-4-yl)pyrrolidin-2-yl)butanoic acid 2,2,2-trifluoroacetate::US10246462, Example 60

SMILES CC(CC(O)=O)[C@@H]1CCCN1C1CCN(CC1C)c1cnc2c(C)nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1

InChI Key InChIKey=YEGUTHPFLGZHCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374679   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374679(US10246462, Example 60 | 3-((2S)-1-(1-(1-((R)-1-(2...)
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
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Date in BDB:
1/21/2020
Entry Details
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