BDBM373685 US9902710, Compound 160

SMILES CCCc1ncc(Cc2ccc3cccc(NC(=O)CN)c3n2)c2cc(OC)c(OC)cc12

InChI Key InChIKey=KBXGASYJJKKANN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373685   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Exonhit Therapeutics

US Patent
LigandPNGBDBM373685(US9902710, Compound 160)
Affinity DataIC50: 15nMAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent