BDBM373272 FD-2013033::US9902709, Compound Example 7

SMILES CNc1c(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccnc1-c1cnn(C)c1

InChI Key InChIKey=BPWPANHJXABLEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373272   

TargetVascular endothelial growth factor receptor 2(Human)
Peking University Founder Group

US Patent
LigandPNGBDBM373272(FD-2013033 | US9902709, Compound Example 7)
Affinity DataIC50: 656nMAssay Description:Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent