BDBM373125 1-[(1S)-1- cyclohexylethyl]-3- (2-methyl-4- phenylpyrimidin-5- yl)urea::US9896447, Compound 41

SMILES C[C@H](NC(=O)Nc1cnc(C)nc1-c1ccccc1)C1CCCCC1

InChI Key InChIKey=IBYKKARFOGQLFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373125   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373125(1-[(1S)-1- cyclohexylethyl]-3- (2-methyl-4- phenyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent