BDBM372334 3,4-dimethyl-N-(2- oxaspiro[3.3]heptan-6- yl)pyrimido[4',5':4,5] furo[2,3-c]pyridazin- 8-amine::US10239887, Cpd. No. 71

SMILES Cc1nnc2oc3c(NC4CC5(COC5)C4)ncnc3c2c1C

InChI Key InChIKey=OYLOEBOVNRBQDR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372334   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372334(US10239887, Cpd. No. 71 | 3,4-dimethyl-N-(2- oxasp...)
Affinity DataEC50: >1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent