BDBM372322 N-[1-(5-fluoropyrimidin-2- yl)azetidin-3-yl]-7,9-dimethyl- pyrido[3',2':4,5]furo[3,2- d]pyrimidin-4-amine hydrochloride::US10239887, Cpd. No. 59

SMILES [2H]c1cc(OC(F)(F)F)cc([2H])c1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccc[n+]([O-])c1

InChI Key InChIKey=VJTWWIBQSOSNCG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372322   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372322BDBM372322(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-2,6...)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent