BDBM372319 7,9-dimethyl-4-(2-oxa-6- azaspiro[3.3]heptan-6- yl)pyrido[3',2':4,5]furo[3,2- d]pyrimidine::US10239887, Cpd. No. 56

SMILES [2H]c1cc(Oc2cc(Cl)c(Cl)cc2C(=O)Nc2ccc[n+]([O-])c2)cc([2H])c1OC(F)(F)F

InChI Key InChIKey=HVNGJFOBKKKHLP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372319   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372319BDBM372319(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-3,5...)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent