BDBM372316 8-chloro-N-(3- methoxypropyl)-7,9- dimethyl-pyrido[3',2':4,5] furo[3,2-d]pyrimidin- 4-amine hydrochloride::US10239887, Cpd. No. 53

SMILES Cc1cc(F)ccc1Oc1cc(C(F)(F)F)c(Cl)c(F)c1C(=O)Nc1cnc[n+]([O-])c1

InChI Key InChIKey=JMDBVGXIHIQKBU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372316   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372316BDBM372316(5-(3-chloro-2-fluoro-6-(4-fluoro-2-methylphenoxy)-...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent