BDBM372306 8-chloro-N,7,9-trimethyl- pyrido[3',2':4,5]furo[3,2- d]pyrimidin-4-amine hydrochloride::US10239887, Cpd. No. 44

SMILES COc1cc(OC(F)(F)F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1cnc[n+]([O-])c1

InChI Key InChIKey=WMEZOXZKCLDWFZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372306   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372306BDBM372306(5-(4,5-dichloro-2-(2-methoxy-4-(trifluoromethoxy)p...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent