BDBM372305 8-chloro-N,N,7,9- tetramethyl-pyrido[3',2':4,5] furo[3,2-d]pyrimidin- 4-amine hydrochloride::US10239887, Cpd. No. 43

SMILES O=C(Nc1ccc[n+]([O-])c1)c1cc(Cl)c(C(F)(F)F)cc1Oc1ccc(SC(F)(F)F)cc1

InChI Key InChIKey=MBUKUGPROKSRMF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372305   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372305BDBM372305(3-(5-chloro-4-(trifluoromethyl)-2-(4- (trifluorome...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent