BDBM372302 8-chloro-N-(2,2- dimethylcyclopropyl)- 7,9-dimethyl- pyrido[3',2':4,5]furo[3,2- d]pyrimidin-4-amine hydrochloride::US10239887, Cpd. No. 40

SMILES O=C(Nc1cnc[n+]([O-])c1)c1cc(Cl)c(C(F)(F)F)cc1Oc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=HLKSDLAHEZOSRG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372302   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372302BDBM372302(5-(5-chloro-2-(4-(trifluoromethoxy)phenoxy)-4-(tri...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent