BDBM372279 4-(azetidin-1-yl)-8- methylpyrido[3',2':4,5] thieno[3,2-d]pyrimidine::US10239887, Cpd. No. 18

SMILES Cc1cnc2sc3c(ncnc3c2c1)N1CCC1

InChI Key InChIKey=VGLAFLSLWYVYEZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372279   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372279(4-(azetidin-1-yl)-8- methylpyrido[3',2':4,5] thien...)
Affinity DataEC50:  807nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372279(4-(azetidin-1-yl)-8- methylpyrido[3',2':4,5] thien...)
Affinity DataEC50:  2.50E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent