BDBM372067 2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)acetamido)methyl)phenyl)-N-methylacetamide::US10239876, Example 90::US10435407, Example 90

SMILES CNC(=O)Cc1cccc(CNC(=O)CN2CN(c3ccccc3)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4c3)C2=O)c1

InChI Key InChIKey=DEVDNVYDNDZDRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372067   

TargetD(1A) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM372067(2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-pheny...)
Affinity DataIC50: 43.1nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM372067(2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-pheny...)
Affinity DataIC50: 43.1nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent