BDBM371856 2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-c]pyridine-5-carbonyl)-1,3,8-triazaspiro[4.5]decan-3-yl)-N-(2,2,2-trifluoroethyl)acetamide::US10239876, Example 20::US10435407, Example 20

SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cc3cn[nH]c3cn2)C1=O

InChI Key InChIKey=VTBIPUIGATVNGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371856   

TargetD(1A) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM371856(2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-c]pyridine-5-...)
Affinity DataIC50: 43.7nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM371856(2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-c]pyridine-5-...)
Affinity DataIC50: 43.7nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent