BDBM371757 N-(pyrimidin-4-yl)-4-(2-(((S)-tetrahydrofuran-3-yl)oxy)-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide::US10239869, Example 183

SMILES FC(F)(F)c1ccc([C@H]2CCOc3cc(ccc23)S(=O)(=O)Nc2ccncn2)c(O[C@H]2CCOC2)c1

InChI Key InChIKey=VZWZWVBDNBJTRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371757   

LigandPNGBDBM371757(N-(pyrimidin-4-yl)-4-(2-(((S)-tetrahydrofuran-3-yl...)
Affinity DataIC50: 11nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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LigandPNGBDBM371757(N-(pyrimidin-4-yl)-4-(2-(((S)-tetrahydrofuran-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent