BDBM371751 (S)-N-(6-fluoropyridin-2-yl)-4-(2-((tetrahydro-2H-pyran-4-yl)oxy)-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide::US10239869, Example 177

SMILES Fc1cccc(NS(=O)(=O)c2ccc3[C@H](CCOc3c2)c2ccc(cc2OC2CCOCC2)C(F)(F)F)n1

InChI Key InChIKey=KUENJSFWXXEVII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371751   

LigandPNGBDBM371751((S)-N-(6-fluoropyridin-2-yl)-4-(2-((tetrahydro-2H-...)
Affinity DataIC50: 11nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM371751((S)-N-(6-fluoropyridin-2-yl)-4-(2-((tetrahydro-2H-...)
Affinity DataIC50: 232nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent