BDBM371736 4-(2-(3-fluoropropyl)-4-(trifluoromethyl)phenyl)-N-(6-fluoropyridin-2-yl)chroman-7-sulfonamide::US10239869, Example 162

SMILES FCCCc1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1cccc(F)n1)C(F)(F)F

InChI Key InChIKey=DNUXZPDEAPDELX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371736   

LigandPNGBDBM371736(4-(2-(3-fluoropropyl)-4-(trifluoromethyl)phenyl)-N...)
Affinity DataIC50: 0.700nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM371736(4-(2-(3-fluoropropyl)-4-(trifluoromethyl)phenyl)-N...)
Affinity DataIC50: 2.64E+3nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent