BDBM37165 1-[4-(3-methoxyphenyl)piperazino]-2-[(5-methyl-2-p-phenetyl-oxazol-4-yl)methylthio]ethanone::2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfanyl]-1-[4-(3-methoxyphenyl)piperazin-1-yl]ethanone::2-[[2-(4-ethoxyphenyl)-5-methyl-4-oxazolyl]methylthio]-1-[4-(3-methoxyphenyl)-1-piperazinyl]ethanone::MLS000120263::SMR000097180::cid_5308111

SMILES CCOc1ccc(cc1)-c1nc(CSCC(=O)N2CCN(CC2)c2cccc(OC)c2)c(C)o1

InChI Key InChIKey=IAOBXTCQCGSRPE-UHFFFAOYSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 37165   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataEC50:  7.42E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataEC50:  1.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataEC50:  9.02E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataIC50: 5.09E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataEC50:  5.87E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataEC50:  4.80E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetTumor necrosis factor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37165(cid_5308111 | 2-[[2-(4-ethoxyphenyl)-5-methyl-1,3-...)
Affinity DataIC50: 4.42E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay