BDBM371641 (R)-N-(5-Fluoropyrimidin-2-yl)-4-(2-(2-methylthiazol-4-yl)-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide::US10239869, Example 66

SMILES Cc1nc(cs1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ncc(F)cn1)C(F)(F)F

InChI Key InChIKey=KQCMZPNLYGCTKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371641   

LigandPNGBDBM371641(US10239869, Example 66 | (R)-N-(5-Fluoropyrimidin-...)
Affinity DataIC50: 8nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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LigandPNGBDBM371641(US10239869, Example 66 | (R)-N-(5-Fluoropyrimidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent