BDBM371020 US10239843, Example 127

SMILES Cc1cc(Cn2c3ccc(cc3c(=O)n(C)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1

InChI Key InChIKey=NBKJIXLCBCPKAW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371020   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM371020(US10239843, Example 127)
Affinity DataIC50: 384nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM371020(US10239843, Example 127)
Affinity DataEC50:  380nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed